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V. Padma ¹, V. Raji Sugumar ²

Affiliations
1 Avvaiyar Government College for Women, Karaikal, Tamil Nadu, IN
2 Bharathidasan Government College for Women, Puducherry, Tamil Nadu, IN

Abstract

The aim of the study is to assess the different baseline biochemical parameters required for type 2 diabetics and to correlate the same with clinical outcomes. Nine hundred Type 2 diabetic subjects aged between 30-85 years of both the genders from 3 diabetic out-patient clinics in South Bangalore were selected for the study. All the study subjects gave their informed consent. All the subjects had clinical examination with anthropometric measurements and measurements of blood pressure. Pre- tested interview schedule was used to collect the information pertaining to socio-economic and duration of diabetes. Biochemical parameters with the laboratory methods done were collected and recorded in the schedule. Among the variables studied, fasting plasma glucose was above 131 mg/dl for 64% of diabetic subjects. Postprandial plasma glucose of >201mg/d1 for 62% and poor to uncontrolled glycosylated hemoglobin (HbA1c) of greater than 8.1% were noted among 38% of the selected diabetic subjects. The individual lipid parameters were also assessed and the diabetic subjects showed higher total cholesterol (29%), triglycerides (33%), Low density Lipoprotein (59%), very Low Density Lipoprotein (15%) and lower High Density lipoprotein levels among 41% selected population. Similarly urine for microalbuminuria was noted in 71% and Albumin Creatinine Ratio (ACR) of >300 microgram/dl was found in 18% of the type 2 diabetic subjects. Also the different biochemical parameters were correlated with HbA1c and it was found that HbA1c was positively associated with all parameters except BMI and HDL at one per cent level (p 5 0.001). The parameters studied indicates that majority of the diabetic subjects are potential to develop diabetic related complications like diabetic nephropathy and underlying cardiovascular disorders. A strict glycemic control and a timely comprehensive evaluation of the biochemical parameters are considered as a potential marker to prevent diabetic prevalence to a certain level.

Keywords

Complications, Lipids, Plasma Glucose, Type 2 Diabetes

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B. Rambabu ¹, V. Padma ², Ramesh Thatikunta ¹, N. Sunil ³

Affiliations
1 Department of Crop Physiology, College of Agriculture, PJTSAU, Telanagana, Hyderabad-30, IN
2 ANGRAU, Bapatla-522101, Andra Pradesh, IN
3 Indian Institute of Maize Research, Rajendranagar, Hyderabad-30, IN

Abstract

Green gram (Vigna radiata L.) Wilczek, chiefly grown as a post rainy season crop, faces water stress situation. A complex response, in terms of biochemical and molecular level is shown by plants, when exposed to drought, and depending on that, plants show differential adaptation and tolerance mechanisms. In the studied biochemical parameters, proline, catalase and peroxidase showed increased activity due to water stress and negatively correlated with seed yield and correlation was significant for catalase and peroxidase, while the total chlorophyll content decreased due to water stress and it was positively and significantly correlated with the seed yield. All the biochemical parameters recorded higher values in genotype WGG 37, whereas, lowest total chlorophyll and leaf proline were recorded in MGG 348 and lowest catalase and peroxidase activity in MGG 347. Highest seed yield was recorded by the genotype WGG 37 (1058.71 kg ha^-1), followed by WGG 42 (1052.22 kg ha^-1), while the lowest seed yield was recorded in MGG 348 (951.42 kg ha^-1). Thus indicating the role of the biochemical parameters and total chlorophyll content in stress mitigation.

Keywords

Green Gram, Total Chlorophyll, Proline, Catalase.

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Rudach Mitul ¹, V. Padma ²

Affiliations
1 1Junior Resident, 2Professor, Dept. of General Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, IN
2 Professor, Dept. of General Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, IN

Abstract

Atherosclerosis, notwithstanding being an illness of lipid gathering, likewise speaks to an incessant provocative procedure⁽¹⁾. Specialists have guessed that incendiary markers, for example, high-affectability C-responsive protein (hsCRP) may give an adjunctive strategy to worldwide appraisal of cardiovascular hazard^(2-4). On the side of this theory, a few huge scale point of view epidemiological investigations have demonstrated that plasma levels of has CRP are a solid autonomous indicator of danger of future fringe blood vessel sickness, Myocardial localized necrosis, stroke and vascular passing among people without known cardiovascular ailment^(4-14). Based partially on these information, high-affectability examines for CRP have befome accessible in standard clinical research centers. Notwithstanding, clinical utilization of hsCRP testing will depend on showing of autonomous prescient worth, yet in addition on exhibit that expansion of hsCRP testing to customary screening techniques improves vascular malady chance expectation. Moreover, utilization of hsCRP as an instrument to aid worldwide hazard appraisal requires information of populace conveyance of hsCRP, clinical attributes of hsCRP assessment, and size of danger of future Peripheral vascular illness that can be normal at each degree of hsCRP. There is a positive relationship between hsCRP levels and T2DM among grown-up rural occupants of South India. This affiliation was free of age, sex, BMI, WC, and WHR, recommending that raised hazard for T2DM probably won’t be constrained to stoutness alone in this populace. Comparable perceptions have been made in past investigations^{(15, 16}. Raised hsCRP levels much of the time group with entrenched hazard components of T2DM, for example, weight and insulin resistance⁽¹⁷⁾. Higher HbA1c levels were seen in all the South Indian subjects with an expansion in hsCRP levels. Likewise, as observed by numerous relapse examination, HbA2c was the significant determinant of hsCRP level in controls. Prior examinations have additionally demonstrated the relationship of raised hsCRP levels with obesity⁽¹⁸⁾ and insulin resistance⁽¹⁹⁾ in North Indian young people and South Indian grown-ups, separately. Relationship of expanding hsCRP levels with expanding fasting insulin, C-peptide, and HOMAIR features concurrence of subclinical irritation and insulin opposition. There is likewise adequate proof to recommend that hsCRP might be related with an expanding danger of future cardiovascular occasions in generally solid individuals⁽²⁰⁾. The aftereffects of the investigation feature the relationship of irritation, as estimated by hsCRP, with T2DM in the rural South Indian populace, free of weight. Corpulence and glycemic controls were distinguished as the real corresponds of hsCRP levels, proposing that the two may have an autonomous impact of foundational aggravation in this populace.

Keywords

T2DM, PAD, hsCRP, Subclinical Irritation, Insulin Opposition.

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B. PRASANNA KUMAR ¹, N. TRIMURTULU ¹, A. VIJAYA GOPAL ¹, V. PADMA ¹, P. MADHU VANI ²

Affiliations
1 Department of Agricultural Microbiology, APGC, ANGRAU, Lam, Guntur - 522 034, Andhra Pradesh, India ., IN
2 Department of Soil Science, Regional Agricultural Research Station, ANGRAU, Lam, Guntur - 522 034, Andhra Pradesh, India, IN

Abstract

Fluorescent pseudomonads drawn broad attention as production of secondary metabolites, phytohormones, siderophores, enzymes, antibiotics, hydrogen cyanide and volatile compounds. The present study was to exhilarate traits of plant growth promotion by fluorescent pseudomonads under drought stress. Fifty one efficient bacterial isolates were taken to evaluate their growth in different concentrations of polyethylene glycol 6000 (PEG) at 0 % (-0.05 MPa), 10 % (-0.65 MPa), 20 % (-1.57 MPa), 30 % (-2.17 MPa) and 40 % (-2.70 MPa). On the basis of growth at higher PEG (40 %) concentration, four efficient bacteria were preferred. Plant growth promoting traits such as IAA, exopolysachharides (EPS) production, ACC deaminase activity, phosphate solubilization and potassium releasing characters were tested for the selected drought tolerant fluorescent pseudomonads. Among four efficient strains, two strains i.e., PCKR-2 showed P-solubilization Index was (3.80 mm), followed by AGVS (4.33 mm), PCKS (4.12 mm) and PVAS (2.28 mm). Data on potassium solubilization activity show that out of two isolates, PCKR-2 showed the highest solubilization zone (3.50 mm), followed by PCKS (3.17 mm), AGVS (2.83 mm) and PVAS (2.50 mm). The findings suggests that the use of fluorescent pseudomonads will aid better plant growth promotion under drought stress.

Keywords

Antibiotics, drought stress, fluorescent pseudomonads, metabolites, polyethylene glycol 6000 .

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